Malabsorption Syndrome Associated with Carcinoma of the Bronchus.

نویسندگان

  • A G WANGEL
  • D J DELLER
چکیده

It is well known that some of the manifestations of carcinoma of the bronchus cannot be explained by the local effects of the malignancy or by distant metastases. The systemic manifestations of malignancy are of importance because they may occur when the lesion in the lung is clinically occult and their study may provide knowledge concerning the biological nature of malignancy itself. Recently a number of metabolic abnormalities have been described: Cushing's syndrome (Kovach and Kyle, 1958); hypercalcaemia (Connor, Thomas, and Howard, 1956); the carcinoid syndrome (Williams and Azzopardi, 1960); and the syndrome of hyponatraemia and persistent renal sodium loss (Schwartz Bennett, Curelop, and Bartter, 1957). Turner and Williams (1962) have reported a case with steatorrhoea as well as hyponatraemia. The tumour was of the oat-cell variety, as appears to be the case with most bronchial carcinomas possessing endocrine activity (McDaniel, Pittman, Hill, and Starnes, 1963). We now report a further case demonstrating the association ofsteatorrhoea and bronchial carcinoma. In our case the steatorrhoea was gross, other features of the malabsorption syndrome were present, sodium metabolism was not affected, and the tumour was a squamous carcinoma. Attempts were made during life and at necropsy to define the cause of the steatorrhoea.

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عنوان ژورنال:
  • Gut

دوره 6  شماره 

صفحات  -

تاریخ انتشار 1965